Hepatotone
$35.95
What This Product Does
- Protects and strengthens your liver so it can work better*
- Boosts your body's natural detoxification defenses*
- Supports healthy bile flow for better digestion and fat absorption*
How to Use
Take 1–2 capsules twice daily with meals.
Key Ingredients
Full Ingredients: Cyperus rotundus (Rhyzome), Aloe barbadensis (Leaf), Solanum nigrum (Fruit), Boerhavia diffusa (Stem, Root), Phyllanthus niruri (Whole plant)
Ayurvedic Energetics
| Rasa (Taste) | Tikta (Bitter) |
| Virya (Potency) | Sheeta (Cooling) |
| Vipaka (Post-digestive) | Katu (Pungent) |
| Dosha Action | Strongly pacifies Pitta and Kapha; may increase Vata in excess |
Science & Research
A triple-action hepatoprotective formula combining three botanicals with independent, evidence-based mechanisms for liver cell protection and regeneration. Picrorhiza kurroa delivers picrosides I and II — iridoid glycosides that demonstrate dose-dependent hepatocyte cytoprotection by stabilizing lysosomal membranes, scavenging superoxide radicals, and enhancing glutathione (GSH) reserves. Phyllanthus niruri's phyllanthin and hypophyllanthin inhibit hepatitis B surface antigen (HBsAg) secretion and modulate hepatic stellate cell activation, potentially attenuating fibrogenic cascades. Andrographis paniculata's andrographolides provide potent choleretic activity and activate Nrf2-mediated antioxidant response element (ARE) transcription, upregulating phase II detoxification enzymes.
Clinical Key Functions
- Hepatic stellate cell modulation attenuating fibrogenesis*
- Nrf2/ARE pathway activation upregulating phase II detoxification enzymes*
- Choleretic activity promoting healthy bile synthesis and flow*
Selected Research
- Floersheim GL, et al. Protective effects of picroliv from Picrorhiza kurroa against Amanita phalloides intoxication in mice. Agents Actions. 1990;29(3-4):386-387.
- Thyagarajan SP, et al. Effect of Phyllanthus amarus on chronic carriers of hepatitis B virus. Lancet. 1988;332(8614):764-766.
- Kapil A, et al. Antihepatotoxic effects of major diterpenoid constituents of Andrographis paniculata. Biochem Pharmacol. 1993;46(1):182-185.
- Stickel F, Schuppan D. Herbal medicine in the treatment of liver diseases. Dig Liver Dis. 2007;39(4):293-304.
Ayurvedic Philosophy
The liver (Yakrit) is the seat of Ranjaka Pitta — the sub-dosha responsible for blood formation, bile production, and the coloring of Rasa Dhatu into Rakta Dhatu. Yakrit Vikara (liver disorders) arise primarily from Pitta Prakopa (Pitta aggravation) combined with Ama (metabolic toxins) accumulating in the hepatic channels (Yakrit Srotas). The treatment follows Pitta-shamana (Pitta pacification), Yakrit Uttejana (liver stimulation), and Ama-pachana (toxin digestion) strategies. Kutki is the foremost Yakrit Shodhak (liver purifier) in the Ayurvedic pharmacopoeia — its intensely Tikta Rasa (bitter taste) is itself considered the most important taste for liver function. Bhumi Amalaki and Kalmegh provide complementary Pittahara and Rechana (purgative) actions to clear vitiated Pitta from the hepatobiliary system.
Classical Text References
- Charaka Samhita, Chikitsa Sthana, Chapter 16 (Pandu Chikitsa) — treatment of hepatic disorders and Ranjaka Pitta vitiation
- Bhavaprakasha Nighantu, Haritakyadi Varga — Katuka (Kutki) classified as Yakrit Uttejaka and premier Pittahara
- Ashtanga Hridayam, Nidana Sthana, Chapter 13 (Pandu-Kamala Nidana) — pathogenesis of hepatic diseases including Kamala (jaundice)